The oral bioavailability of many botanical extracts
is erratic and poor due to limited gastro-intestinal absorption, degradation at intestinal pH, and extensive intestinal metabolization.
Bioavailability can be improved by using new delivery systems which can enhance the rate and the extent of solubilization into aqueous intestinal fluids and the capacity to cross biomembranes.
Phospholipids exhibit a marked affinity for polyphenols. By combining in a suitable molar ratio polyphenols and phosphatidylcholine, Indena has developed a new line of non-covalent supramolecular adducts named “Phytosome®s”(1,2).
Phytosome®s show better pharmacokinetic and therapeutic profile than their non-complexed herbal extracts.
The Phytosome®s technology, enhances the bioavailability of selected phytochemicals.
Please note that this web site is not aimed at consumers as the information herein contained does not make reference to finished products. Please note this website is accessible from various countries all over the world and hence it may contain statements or product classification not applicable to your country. The claims made are in reference to ingredients only, hence they do not refer to finished products and they may not comply with Regulation 1924/2006/CE. The marketer of any finished product containing any ingredient is responsible for assuring that the destination of the product and the claims made for the finished product are lawful and comply with all applicable laws and regulations of the country or countries in which the product is to be sold.
1. Semalty A, et al, Supramolecular
phospholipids–polyphenolics interactions: The PHYTOSOME®
strategy to improve the bioavailability of phytochemicals, Fitoterapia (2009).
2. Kidd PM., Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts, Altern Med Rev. 2009 Sep;14(3):226-46.